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BIOL122 Human Biological Science
Questions:
Student Instructions:
You will have the opportunity to describe the pathophysiology and pharmacological management for a person/client suffering from diabetes mellitus (type I, type II, or gestational) or extrinsic bronchial asthma.
We expect you to show your understanding by making explicit links between pathophysiology, clinical manifestations, and pharmacological management of your person/client’s disease.
When preparing your presentation, assume that your target audience is health professionals (e.g., nurses, paramedics, midwives; all of which should have roughly the same base knowledge). Your answers to the questions below will be used to grade the ‘depth’, ‘accuracy’, and ‘clarity’ sections of your Vodcast assignment (see marking rubric provided at the end of this document).
At the beginning of your Vodcast, you need to set the scene within the first minute by introducing your patient. Following this introduction, proceed to answer the following questions.
DIABETES MELLITUS
You must answer all questions below:
Question 1a
Explain how both of the following are different in your patient in comparison to a healthy, non- diabetic person:
- Insulinsynthesis and secretion; and
- Insulinbinding to its target
Question 1b
Explain the benefits of monitoring HbA1c in the management of your person’s/client’s disease.
Question 2a
Neuropathy and myocardial infarction are long-term consequences of poorly managed diabetes. Explain why they are more likely to occur in patients suffering from diabetes than in the non- diabetic population.
Question 2b
Both metformin and insulin may be used in the management of diabetes mellitus. By making meaningful references to your patient,
- Choosethe one that is the most appropriate for the treatment of your patient,
- Describethe mechanism of action of your choice, and
- Explainwhat makes the drug you selected the most appropriate for the treatment of your
Question 3
Define insulin resistance and explain the link between apple-type obesity and insulin resistance
Extrinsic Bronchial Asthma You must answer all questions below:
Question 1
Two of the major pathological changes that affect the airways during an asthma attack are bronchoconstriction and increased mucus production in the airways. By reflecting on the pathophysiology of bronchial asthma.
explain how these pathological changes arise in your patient. In your explanation, you are expected the outline the significance of a specific allergen that may trigger an acute asthma attack.
Question 2a
The clinical manifestations of an acute asthma attack may include the following signs and symptoms:
|
GROUP A |
GROUP B |
|
Cough |
Airway oedema |
|
Hypoxia |
Increased respiratory rate |
|
Wheeze |
Increased heart rate |
|
Tight chest |
Dyspnoea |
Choose one clinical manifestation from GROUP A and one from GROUP B and relate them to the underlying pathophysiology for your person. In your answer, explain the link between an acute asthma attack and both signs/symptoms you chose.
Question 2b
Salbutamol and corticosteroids are used in the management of asthma. Explain the mechanism of action of these two medications and their benefits in managing your patient’s condition.
Question 3
Adequate education of patients suffering from/prone to asthma attacks is important in asthma management. Briefly summarize the advice you would give to your patient in respect to
- Corticosteroidadministration and
- Strategies relating to effective prevention and management of their acute asthmatic
BIOL122 Human Biological Science
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