BCH3ATB: An aging, pathology burden, and glial senescence build-up hypothesis for late onset Alzheimer’s disease: Marking Rubric for “News and Views” Assignment, NIH
An aging, pathology burden, and glial senescence build-up hypothesis for late onset Alzheimer’s disease Abstract: Alzheimer’s disease (AD) predominantly occurs as a late onset (LOAD) form involving neurodegeneration and cognitive decline with progressive memory loss. Risk factors that include aging promote accumulation of AD pathologies, such as amyloid-beta and tau aggregates, as well as inflammation … Read more