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NURS 6501: Week 7 Quiz Question 2 / NURS-6501N Advanced Pathophysiology

 

NURS 6501: Week 7 Quiz:

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Question 2

Which of the following is best described as a monophasic disseminated CNS inflammatory disorder?

Group of answer choices

  • Transverse myelitis
  • Acute disseminated encephalomyelitis (ADEM)
  • Optic neuritis
  • Multiple sclerosis

 

Correct answer: Acute disseminated encephalomyelitis (ADEM)

 

Explanation:

Acute disseminated encephalomyelitis (ADEM) is a monophasic, immune-mediated, inflammatory demyelinating disease of the central nervous system (CNS) that typically occurs after a viral infection or vaccination, especially in children and young adults.

Key features of ADEM:

  • Monophasic (single episode, not relapsing)
  • Widespread CNS demyelination
  • Often follows a preceding infection or immunization
  • Symptoms: encephalopathy, seizures, motor/sensory deficits, ataxia, etc.
  • MRI shows diffuse, bilateral, asymmetric white matter lesions

 

Why the other options are incorrect:

  • Transverse myelitis
    → Inflammation of the spinal cord, may occur as part of a monophasic or multiphasic disorder, but not disseminated across the CNS
  • Optic neuritis
    → Inflammation of the optic nerve; typically focal, and often associated with multiple sclerosis
  • Multiple sclerosis (MS)
    Chronic, relapsing-remitting or progressive, disseminated CNS disorder — not monophasic

 

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