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NURS 6501: Week 7 Quiz Question 9 / NURS-6501N Advanced Pathophysiology

 

NURS 6501: Week 7 Quiz:

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Question 9

In the progression of Alzheimer disease, specific regions of the brain are preferentially affected. Which region is typically first impacted in the early stages of Alzheimer disease?

  • Occipital lobe
  • Frontal lobe
  • Medulla oblongata
  • Temporal lobe

Correct answer: Temporal lobe

 

Explanation:

In Alzheimer disease, the early pathological changes begin in the medial temporal lobe, specifically affecting:

  • The hippocampus
  • The entorhinal cortex

These areas are crucial for memory formation, which explains why short-term memory loss is often the earliest clinical symptom in Alzheimer’s disease.

 

Breakdown of options:

  • Temporal lobe ✅
    ✔ First affected (especially hippocampus) → causes memory loss.
  • Occipital lobe ❌
    ✘ Involved much later; associated with visual processing.
  • Frontal lobe ❌
    ✘ Affected in later stages; responsible for executive function and personality.
  • Medulla oblongata ❌
    ✘ Controls basic life functions (e.g., breathing, heart rate) and is not primarily involved in Alzheimer’s.

 

Key point:
Memory loss is a hallmark of early Alzheimer’s, and that reflects temporal lobe (hippocampal) involvement.

 

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