Homework Help Question & Answers
What benefit can human stem cells provide to individuals with a genetically determine immunodeficiency? How would…
- What benefit can human stem cells provide to individuals with a genetically determine immunodeficiency? How would the process work? Can individuals receive their own stem cells?
-
Fill in the blanks with the missing information about primary and secondary lymphoid organs:
The ___________ is the site of T cell development and maturation. The ________ is the site of B cell differentiation and hematopoesis.
The ___________ are the sites where immune responses are mounted to antigens in the lymph. The _____________ is where immune responses are mounted to antigens in the blood. The ___________ is lymphoid tissue that responds to antigen in the digestive, respiratory, and urogenital systems. Epithelial cells lacking microvilli that transport the antigens to these tissues are known as ________.
- Describe the structure of the B-cell receptor (BCR). How is the BCR able to trigger a signal transduction pathway when its cytoplasmic tail is only 3 amino acids in length? Outline BCR signal transduction from the point of antigen binding through the NF-κB pathway. What is the result of signal transduction events from the BCR?
- What is agammaglobulinemia? What enzyme is mutated in these patients and what is this enzyme’s function? What happens to people with this disorder?
- What is Lck and why is it important? What would happen to a T cell if a mutation were introduced in Lck?
- Define the following and give an example for each:
- cytokine
- interleukin
- chemokine
- chemoattractant
Add a comment
