#1 Describe in your own words a clinical population based problem you would like to examine. With words and data, define and describe the population. Explain why you think it is important to address this problem. Write a clinical question using the PICO format. Recall, the acronym stands for population studied (P), intervention (I), comparison (C), and outcome (O). These are the key components of a well-focused question. #2 How can innovative application of health information technology improve population health and what are the benefits to patients and providers with meaningful use?