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The Stork reaction is a condensation reaction between an enamine donor and an a,B-unsaturated carbonyl acceptor….


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The Stork reaction is a condensation reaction between an enamine donor and an a,B-unsaturated carbonyl acceptor….

The Stork reaction is a condensation reaction between an enamine donor and an a,B-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of 1. formation of an enamine from a ketone, 2. Michael addition to an a,B-unsaturated carbonyl compound, and 3. hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between acetophenone and 3-buten-2-one. 1 Draw the structure of the product of the enamine formed between acetophenone and dimethylamine. N – O -/ -000-F HzCYCH; YCH
2 Draw the structure of the Michael addition product. ChemDoodle
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